The Efficacy and Safety of Korean Herbal Medicine in a Patient with Endometrioma of The Ovary: A Case Report.

OBJECTIVE: The objective of our study is to report our experience of treatment of a patient with endometrioma who was diagnosed with blood deficiency and blood stasis. METHODS: A 36-years-old Korean woman diagnosed with endometrioma of the right ovary complained of pelvic pain around the menstrual periods, vaginal discharge, and swelling and itching of the pudenda. The patient was administered the modified Gyejibokryeong-hwan (GBH) and the Bogol-gongjin-dan (BGD) for 6 months. RESULTS: After treatment, the size of the endometrioma in the right ovary was reduced to 17 × 11 × 10  mm from 25 × 21 × 17  mm before treatment. The level of CA 125 decreased from 47.2 U/ml at baseline to 34.3 U/ml after treatment. The level of CA 125 after treatment was within normal range. After treatment, the pelvic pain around the menstrual periods (VAS 7→1), vaginal discharge (VAS 4→1), and swelling and itching of the pudenda (VAS 5→2) decreased from the baseline values. CONCLUSION: Herbal medicine is a potential alternative therapy for patients with endometrioma of the ovary. Further studies, including case-control studies and RCTs based on an international standard and higher methodological quality, are needed.