Nucleic Acid Detection of Fecal Samples from Confirmed Cases of COVID-19

To investigate the status of viral infection in the feces of confirmed COVID-19, cases fecal samples or anal swabs from 36 patients were collected, SARS-CoV-2 was detected by real-time fluorescence RT-PCR, and the infection rates of the cases were compared by statistical analysis software SPSS 19 0 Among the 36 samples, 20 (55 56%) were positive for SARS-CoV-2 The positive rate of critical cases (2/3) and severe cases (6/9) were both 66 67%, the positive rate of common pneumonia was 62 50% (10/16), and the positive rate of mild pneumonia was 25 00% (2/8) The 36 confirmed COVID-19 cases included 22 males and 14 females, with a detection rate of 54 55% and 57 14%, respectively The age distribution range of the cases was between 17 and 86 years old, with an average age of 48 75 years Among the 36 samples, 2 positive specimens were detected in 5 anal swab specimens and 18 positive specimens in 31 fecal specimens There were no statistically significant differences in the positive detection rates among clinical typing, gender, age and specimen type, respectively From these results, we deduced that fecal samples of confirmed COVID-19 cases contained SARS-CoV-2, which can cause infection through potential fecal-oral transmission and be significant for clinical treatment and epidemiological study