CaOx Stone Prevention

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
This single-center randomized controlled trial at Mount Sinai West will enroll 80 patients undergoing percutaneous nephrolithotomy for calcium oxalate stones. Participants will be randomized to receive either empiric therapy or selective therapy guided by 24-hour urine evaluation. The primary outcome is change in calcium oxalate supersaturation at 4 weeks, aiming to determine whether empiric therapy can provide outcomes comparable to selective therapy while simplifying access to prevention.
Epistemonikos ID: 81fc38f38904371043948089691f48eb30f61e9c
First added on: Nov 11, 2025