Comparison of Aprepitant Versus Gabapentin in the Prevention of Delayed Nausea and Vomiting

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2004
1. To compare the effectiveness of gabapentin (titrated to300mg TID days -2 to 5) with aprepitant (125mg on day 1 and 80mg on days 2 and 3) in the control of delayed nausea and vomiting associated with level 3, 4 or 5 emetogenic chemotherapy in patients who experienced delayed nausea and/or vomiting during their first cycle of chemotherapy. 2. To evaluate and compare the safety profile associated with each anti-emetic regimen. 3. To assess subject satisfaction with anti-emetic therapy.
Epistemonikos ID: 81e78c4c58eba33a1da81ce4511b1fea3a8412b5
First added on: May 04, 2024