The effects of propranolol on fear of wisdom tooth removal: a randomized, placebo-controlled, double-blind, parallel design trial

INTERVENTION: At day one: Dental treatment (fillings, root canal treatments, extractions) and randomization to either: 1. Propranolol 80 mg prior to, and 40 mg directly after treatment, or; 2. Placebo 80 mg prior to, and 40 mg directly after treatment. At day 30: Dental treatment (fillings, root canal treatments, extractions). CONDITION: Dental phobia, Specific phobia, blood‐injection‐injury type ; ; PRIMARY OUTCOME: 1. Dental anxiety (as measured by the short version of the Dental Anxiety Scale; S‐DAI);; ; 2. Emotional disregulation in reaction to exposure to traumatic memory (as measured by the Impact of Event Scale Revised; IES‐R). SECONDARY OUTCOME: 1. Visual analogue scales (VASs) for anxiety, various emotions and pain during treatment; ; ; 2. Physiological parameters (heartrate and bloodpressure). INCLUSION CRITERIA: 1. Fulfilling the diagnostic criteria for Specific Phobia, blood‐injury‐injection type according to the DSM‐IV‐TR; 2. Age above 18 years.