Blood pressure-oriented versus blood flow-oriented circulatory management for preventing intraventricular hemorrhage in VLBW infants during first 7 days: a randomized trial

INTERVENTION: blood pressure‐oriented group: administering circulatory agent aiming to keep blood pressure above the number of gestational age blood flow‐oriented group: administering circulatory agent aiming to keep blood flow above the cut‐off values obtained by previous study CONDITION: cardiovascular failure in very low birth weight infants PRIMARY OUTCOME: incidence proportion of intraventricular hemorrhage SECONDARY OUTCOME: 1. mortality during neonatal period; 2. mortality at 1 year of age; 3. incidence proportion of periventricular leukomalacia; 4. incidence proportion of necrotizing enterocolitis; 5. incidence proportion of retinopathy of prematurity; 6. proportion of infants who received any kinds of circulatory support; 7. proportion of infants who could not achieve the goal of therapies (blood pressure or blood flow) INCLUSION CRITERIA: Very low birth weight infant (less than 1500g of birth weight)