Clinical Efficacy and Mechanism of Ketogenic Diet in Patients with Migraines

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Ketogenic diet intervention group:Strictly standardized ketogenic diet intervention;Group without any special dietary interventions:No special diet needed, just keep your usual eating habits.; CONDITION: migraine PRIMARY OUTCOME: Frequency of headache attacks;VAS scale score; SECONDARY OUTCOME: Sleep Quality Self‐Assessment Scale (SRSS) score;HIT‐6 scale score;Blood ketone levels in the fingertip blood;CGRP levels; INCLUSION CRITERIA: 1. Age: 18 to 60 years old; 2. Patients who were diagnosed with migraine before enrollment (in accordance with the “Chinese Guidelines for the Diagnosis and Treatment of Migraine (1st edition of the Neurology Branch of the Chinese Medical Association”); 3. Improve cranial CT/MR imaging to rule out any organic intracranial lesions. 4. The patient or their legal representative voluntarily participates in this trial and signs the informed consent form.
Epistemonikos ID: 7fbd3422aae233f3ddc914995c9eec8fa33e5e66
First added on: Oct 08, 2026