Eating nuts while breastfeeding – the Nuts For Babies Study.

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2024
INTERVENTION: Maternal consumption of at least 60 peanuts and 40 cashew nuts per week from birth until 6 months post‐natal. Participants will purchase their own peanuts and cashew nuts. Every 2 weeks during the intervention period, the women will be sent a mobile phone text with a link to complete a quick survey about how much peanut and cashew nut they have eaten over the past week, and whether they would like any further advice and support regarding their allocated nut diet. This will also include one question on their breastfeeding status. CONDITION: IgE‐mediated peanut allergy;IgE‐mediated cashew nut allergy; ; IgE‐mediated peanut allergy ; IgE‐mediated cashew nut allergy Inflammatory and Immune System ‐ Allergies PRIMARY OUTCOME: The proportion of infants with IgE‐mediated peanut and/or cashew nut allergy ‐ this is a composite primary outcome.[Positive peanut/cashew nut allergen skin prick test and positive peanut/cashew nut oral food challenge. At 12 months of age] SECONDARY OUTCOME: The proportion of infants with a medical diagnosis of eczema [Parent report that a medical practitioner has diagnosed infant eczema. At 3, 6, 9 and 12 months of age] The proportion of infants with allergic sensitisation to almond [Positive almond allergen skin prick test At 12 months of age] The proportion of infants with allergic sensitisation to cashew nut [Positive cashew nut allergen skin prick test At 12 months of age] The proportion of infants with allergic sensitisation to hazelnut[Positive hazelnut allergen skin prick test At 12 months of age] The proportion of infants with allergic sensitisation to peanut [Positive peanut allergen skin prick test At 12 months of age] The proportion of infants with IgE‐mediated cashew nut allergy[Positive cashew nut allergen skin prick test and positive cashew nut oral food challenge At 12 months of age] The proportion of infants with IgE‐mediated peanut allergy [Positive peanut allergen skin prick test and positive peanut oral food challenge At 12 months of age] INCLUSION CRITERIA: Women with a singleton pregnancy, who are planning to breastfeed, and where the infant has a high‐risk of developing nut allergies due to a family history of eczema/atopic dermatitis, IgE‐mediated food allergy and/or hay fever (allergic rhinitis) in at least one of the infant’s biological parents (mother and/or father) or full‐sibling (child with the same biological mother and father).
Epistemonikos ID: 7fa0bd564d0ca707acb409da691ebb71f0d037a4
First added on: Aug 28, 2024