Study of Comparing the Different Effect of DPP-4 Inhibitors and Sulfonylurea by Using "Biphase-Hyperglycemic Clamp"

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2012
The objective of this study is to demonstrate the different effects of two DPP-4 inhibitors(Sitagliptin, Saxagliptin)and the insulin secretagogue: glimepiride on first and second phase insulin secretion by using a Biphase-Hyperglycemic Clamp and to explore the different effects of the study drugs on the GLP-1 response, and the glucagon concentration which indicates alpha cell function in healthy subjects.
Epistemonikos ID: 7f8e6751c1c6c8b8a55d139a89a4421d9d1c6696
First added on: May 11, 2024