Amitriptyline versus Carbamazepine in the treatment of painful diabetic neuropathy

INTERVENTION: Amitriptyline, 50 mg/day (daroupakhsh) for 6 weeks Carbamazepine, 600 mg/day (Sobhan darou) for six weeks Intervention 1: Amitriptyline, 50 mg/day (daroupakhsh) for 6 weeks. Intervention 2: Carbamazepine, 600 mg/day (Sobhan darou) for six weeks. Treatment ‐ Drugs CONDITION: Diabetic polyneuropathy painful diabetic neuropathy. ; Diabetic polyneuropathy PRIMARY OUTCOME: Painful neuropathy. Timepoint: 6 weeks. Method of measurement: brief pain inventory (quantitative scale). SECONDARY OUTCOME: Drugs complications. Timepoint: 6 weeks. Method of measurement: by history and assessment. INCLUSION CRITERIA: INCLUSION CRITERIA: age 18‐65 y/o, confirmed diabetic neuropathy with EMG/NCV Exclusion criteria: pregnancy, breast feeding, recent MI, allergy to drugs, past hx. of seizure, mood disorder, diabetic cystopathy or gastroparesis, renal or hepatic failure, hypothyroidism.