Effect of Respiratory Muscle Training in Multiple Sclerosis

INTERVENTION: Intervention 1: Intervention group:?They will educated respiratory muscle training with a pressure threshold device (Power‐breath), then patients will do exercises for 8 weeks. During this time, patients will be followed up by telephone and the intensity of the device will be increased on a weekly basis. Intervention 2: Control group: ?They will be explained about the training and importance of regular physical activity in MS patients and lifestyle modification, and will be given a booklet on the subject. During the program, patients receive their usual medication as before. CONDITION: Multiple Sclerosis. ; Multiple sclerosis PRIMARY OUTCOME: Maximum Expiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine. Maximum Inspiratory Pressure. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Body Box machine. SECONDARY OUTCOME: Aerobic capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Six Minute Walk Test (6MWT). Fatigue. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Modified Fatigue Impact Scale questionnaire (MFIS). Forced Expiratory volume in the first second (FEV1). Timepoint: before intervention and 8 weeks after interventio. Method of measurement: Spirometry. Forced Expiratory volume in the first second (FEV1)/Forced Vital Capacity (FVC). Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Spirometry. Functional capacity. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: Timed Up and Go test (TUG). Quality of Life. Timepoint: before intervention and 8 weeks after intervention. Method of measurement: SF‐36 questionnaire. INCLUSION CRITERIA: Definite diagnosed relapsing‐remitting MS Year after diagnosed at least one year Be able to walk without support at least 10 meters Not have an relapse at least one month Taking no intravenous corticosteroid drug