Comparative study between a phytotherapeutic and chlorhexidine on alveolar healing

INTERVENTION: E06.892 In present study, the sample consisted of 30 patients, aged between 18 and 60 years, of both genders, who were divided into 2 groups, each with 15 patients. After the extracion, 150 mL of protocol 1 (Chlorhexidine 0.12%) or protocol 2 (Elixir Sanativo ‐ phytotherapic) was given to evaluate the following parameters: pain, bleeding, hyperemia, necrosis and analgesic use). Along with the postoperative guidelines, the patient was instructed to sanitize the extraction region 3 times daily after brushing with local application of the chosen protocol soaked in a gauze for 7 days. They returned after 24 hours for pain evaluation through the Visual Analogue Scale (VAS) and after 7 days for clinical evaluation of the criteria of healing (bleeding, hyperemia and necrosis) and pain, through VAS. After evaluation and removal of the suture, the patient subject a new contralateral tooth extraction, where the same previous procedures were performed, but with the other protocol medication. Exodontitis was performed by the same operator following the Marzola protocol (1999) and all patients were anesthetized with 2% lidocaine hydrochloride with epinephrine 1: 100,000 not extrapolating 2 tubes following the protocol of Malamed (2005). The prescribed postoperative analgesic medication was Dipirone Sodium (500mg) and directed to take only in case of pain. At the end was noted the number of days and amount of analgesics used in each protocol. All patients were reminded daily about the hygiene of the region with the drug through the connections made by the researcher. CONDITION: G16.762.891 Wound Healing ; G16.762.891 PRIMARY OUTCOME: Expected Outcome 1 ‐ Chlorhexidine presents better results in comparison to the phytotherapic in the clinical criteria analyzed: bleeding, necrosis and hyperemia after 07 days of the surgical procedure Expected outcome 2 ‐ Due to its analgesic properties, Phytotherapy shows better results compared to chlorhexidine in the pain parameter (through the visual analogue scale) after 24 hours and 07 days of the surgical procedur Found Outcome 1 ‐ There was no difference between chlorhexidine and phytotherapic in the clinical criteria analyzed (bleeding, necrosis and hyperemia) after 07 days of the surgical procedure Found outcome 2 ‐ There was no difference between chlorhexidine and phytotherapic in the pain parameter, after 24 hours and 07 days of the surgical procedure SECONDARY OUTCOME: Secondary outcomes are not expected INCLUSION CRITERIA: systematically healthy patients; indication for contralateral tooth extraction from extensive carious lesion, periodontal disease or orthodontic indication, without osteotomy or odontosection