Acupuncture Therapy for Chemotherapy-Related Peripheral Neuropathy: A Multicenter Randomized Controlled Clinical Tria

INTERVENTION: Electroacupuncture Group:Acupoints: Hegu, Quchi, Zusanli, Taichong, Baxie, Bafeng. Procedure: Insert needles perpendicularly or obliquely until de qi is achieved, then connect to electroacupuncture device delivering sparse‐dense wave or continuous wave (2‐100 Hz), retain needles for 30 minutes, with needle manipulation every 10 minutes. Treatment course: 8 weeks, total of 20 sessions (3 times per week for the first 4 weeks, 2 times per week for the last 4 weeks).;Sham Acupuncture Group:Acupoints: Non‐acupoints. Procedure: Superficial insertion (approximately 2‐3 mm) at non‐acupoints, connect to electroacupuncture device but no current output. Retain needles for 30 minutes. Treatment course: 8 weeks, total of 20 sessions (3 times per week for the first 4 weeks, 2 times per week for the last 4 weeks).; CONDITION: Chemotherapy‐related peripheral neuropathy PRIMARY OUTCOME: CIPN Remission Rate at Week 8 (Proportion of Patients with NRS Score Decreased by =30% from Baseline); SECONDARY OUTCOME: CIPN20 Scale;Numerical Rating Scale (NRS) Score;NCI‐CTCAE Grading;Quality of Life Scale (FACT‐G/EORTC QLQ‐C30);Electromyography (EMG);Magnetic Resonance Neuroimaging;Neurosonography;Safety Outcomes (Including Needle‐Related Adverse Events such as Infection, Hematoma, Syncope, Other Adverse Events, and Serious Adverse Events [SAEs]); INCLUSION CRITERIA: 1. 18 years old <= age <= 80 years old; 2. Diagnosed with cancer, using platinum‐based or taxane‐based drugs, with an expected lifespan of more than 1 year; 3. Willing to accept electroacupuncture treatment; 4. No history of peripheral neuropathy, and no symptoms or signs of peripheral nerve damage after chemotherapy; 5. Normal intelligence, able to complete the assessment scales.