Prospective, randomized, double-blind, controlled, multi-center clinical study for Hushen Yiqi Granule in the treatment of IgA nephropathy

INTERVENTION: control group:Basic treatment of Western Medicine;experimental group:Hushen Yiqi Granule combined with basic treatment of western medicine; CONDITION: IgA nephropathy PRIMARY OUTCOME: ;Proteinuria increased by 50% from baseline ; SECONDARY OUTCOME: New onset of cardiovascular events requiring hospitalization;New onset of infection requiring hospitalization;Patient enter the ESRD stage ; INCLUSION CRITERIA: 1. Pathological diagnosis of patients with IgA nephropathy; 2. 24‐hour urine protein quantitation >= 1.0g (two tests, interval > 7 days), or CKD 2‐4; 3. Aged 18‐80 years; 4. Sign the informed consent form.