Examination of suppressive effect by combined treatment of orthokeratology and atropine 0.01% ophthalmic solution on myopia progression

INTERVENTION: Orthokeratology contact lens Atropine 0.01% ophthalmic solution CONDITION: Myopia PRIMARY OUTCOME: Efficacy: Increase in axial length over a 2‐year period SECONDARY OUTCOME: Safty: Decrease in corneal endothelial cell density over a 2‐year period; Efficacy: Increase in axial length over a 1‐year period; Safty: Decrease in corneal endothelial cell density over a 1‐year period INCLUSION CRITERIA: 1) Cycloplegic spherical equivalent refractive error of ‐1.00 to ‐6.00 D in both eyes 2) Astigmatism of less than 1.50 D in both eyes 3) Anisometropia of less than 1.50 D 4) Best corrected visual acuity of more than 1.0 in both eyes