DHEA in Synovial Sarcoma Patients

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2016
DHEA is a natural allosteric inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PD is a key regulatory enzyme for the survival of synovial sarcoma. The investigators postulate that they can inhibit the production of NADPH in synovial sarcoma and cause cell death by using a naturally occurring G6PD inhibitor.
Epistemonikos ID: 7ba94e2cb4617b07e9f4f5cfdce76a9fbc420a17
First added on: May 12, 2024