The Effects and Mechanisms of Mindfulness-Based Resistance Training on Depression and Anxiety in Colorectal Cancer Patients through Interoception

INTERVENTION: Mindfulness intervention group:Participants will receive mindfulness‐based intervention sessions according to the approved protocol.;Resistance Exercise group:Participants will receive resistance training according to prescribed FITT‐VPD parameters.;Mindfulness‐based slow‐speed resistance training group:Participants will receive an integrated mindfulness and slow‐speed resistance training intervention according to the approved protocol; CONDITION: Colorectal Cancer with Depression symptoms PRIMARY OUTCOME: Depression symptoms; SECONDARY OUTCOME: Anxiety symptoms;Insomnia symptoms;Mindfulness;Interoceptive Awareness;Interoceptive Attention and Accuracy;Gastrointestinal Interoception;Behavioral automaticity; INCLUSION CRITERIA: INCLUSION CRITERIA: participants were eligible for inclusion if they were between 18 and 65 years of age and were colorectal cancer patients with stage I to III disease. All participants were required to be at least 10 weeks post‐operative from any cancer‐related surgical procedure and to exhibit clinically meaningful depressive symptoms, defined by a PHQ‐9 score greater than 10. Only individuals who were able to ambulate independently without assistance and who had normal or corrected‐to‐normal vision and adequate hearing were considered. Eligible participants also needed to express a clear willingness to engage in the full 12‐week intervention and follow‐up assessments. Finally, enrollment was limited to those who, according to the American College of Sports Medicine (ACSM) pre‐exercise screening questionnaire, had no contraindications to participating in structured exercise