Efficacy Evaluation Of Skin Fairness Creams On Healthy Human Volunteers

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2011
INTERVENTION: Intervention1: Fairness Cream A Fairness Cream B Fairness Cream c Fairness Cream D Fairness Cream E Fairness Cream F Fairness Cream G Fairness Cream H : All these Investigational products are cosmeceutical products. The study aims at assessing the investigational products for their ability to increase skin fairness, hydration, elasticity, firmness, smoothness and softness and reduce fine lines and wrinkles, hyper‐pigmentation/dark/ age spots and sun induced skin tanning. All creams are topical, The creams are been assigned to Patients based on randomization. Each product would be received by at least 35 subjects.0.2‐0.5 ml will be applied on face twice a day topically all over the face. Duration‐ 6 weeks per subject Intervention2: Fairness Cream A Fairness Cream B Fairness Cream c Fairness Cream D Fairness Cream E Fairness Cream F Fairness Cream G Fairness Cream H: All creams are topical, The creams are been assigned to Patients based on randomization. Each product would be received by at least 35 subjects.0.2‐0.5 ml will be applied on face twice a day topically all over the face. Control Intervention1: Controls For The Study Placebo Cream : Comparison to baseline. Comparison to other investigational products. Control Intervention2: Control site: Sun unexposed, untreated site on upper volar bicep region : Comparison to baseline. Comparison to other investigational products. CONDITION: Normal Condition PRIMARY OUTCOME: 1)To evaluate the efficacy of fairness cream formulations in conferring skin fairness, radiance and glow, moisturization, softness, smoothness and healthy appearance in comparison to baseline and to other investigational products.2)To evaluate the efficacy of fairness cream formulations in reducing Sun induced tanning and associated photodamage in terms of dark spots and wrinkling in comparison to baseline and to other investigational products.‐‐‐‐‐‐Timepoint: 6 Weeks SECONDARY OUTCOME: ? To evaluate the safety of fairness cream formulations on all skin types including acne prone skin. ; ; ? To evaluate the efficacy of fairness cream formulations in conferring even tone, clear skin, young appearing skin in comparison to baseline, placebo and other investigational products.‐‐‐‐‐‐Timepoint: 6 Weeks INCLUSION CRITERIA: Subjects willing to give a written informed consent and come for regular follow up. Female subjects in generally good health, in the age group of 18 ‐ 45 years. Subjects having Chromameter L value between 40‐60 on cheeks and L value at least 3 units higher than the cheeks on upper volar bicep region. Subject, who get Sun exposure for atleast 20‐40 mins per day. At least 5 subjects under each treatment group having acne prone skin. At least 5 subjects under each treatment group having few hyper‐pigmentation spots on face like solar lentigines and /or post acne dark spots other than melasma/ nevi etc. Subjects willing to abstain from using other cosmetic/ medicinal/ ayurvedic/ natural products on face during the study course.
Epistemonikos ID: 7b15273b023536008babc50b9046d49872fe2ad6
First added on: Aug 22, 2024