Topical Application of Tranexamic Acid Compared to the Intravenous Administration in Total Hip Arthroplasty With the Direct Anterior Approach A Prospective, Randomized, Clinical Trial

Through a randomized controlled trial, we will compare the intravenous administration of tranexamic acid with the intra-articular application after a total hip arthroplasty through direct anterior approach. * RCT, prospective study * Academic-monocentric study * Clinical outcome measurements The postoperative blood loss will be the primary outcome. Secondary outcomes are 1. The rate of perioperative and postoperative blood transfusion 2. The number of blood units transfused 3. The length of hospital stay 4. Perioperative given intravenous isotonic fluid The Null-hypothesis is that there is no significant difference in postoperative blood loss between intra-articular and intravenous administration of TXA.