Early Targeted Antibiotic Therapy in Patients With Sepsis

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2022
The aim of this study is to assess the efficacy of early targeted antibiotic therapy in patients with sepsis and septic shock using the new biomarker Sirtuin 1 and PCR for bacterial resistance detection. The primary outcome is change in SOFA score (ΔSOFA) which will be calculated by subtracting the final SOFA score and sirtuin 1 level at 5 days from the corresponding initial value at enrollment. Secondary outcomes included mortality rates, ventilator free days and length of icu stay.
Epistemonikos ID: 78deeb2d51a55a45fb5525c5951236f5bc451f17
First added on: May 13, 2024