Comparison of the efficacy and safety of oxazepam and diazepam in the treatment of acute withdrawal symptoms of alcohol dependence A multicenter practical randomized controlled study (pRCT)

INTERVENTION: Diazepam group:Patients in the diazepam group were treated with oral diazepam, following the fixed dosing regimen until the CIWA‐Ar score was <=8 points, and then the medication was stopped.administration. ;The oxazepam group:Patients in the oxazepam group were treated with oral oxazepam, following the fixed dosing regimen until the CIWA‐Ar score was <=8 points, and then the medication was stopped.; CONDITION: AWS PRIMARY OUTCOME: Change in CIWA‐Ar score and time to reach a score of <=8; SECONDARY OUTCOME: Trends in liver function indicators; INCLUSION CRITERIA: 1. Inpatients; Aged 18 to 70; 2. Meet four or more of the DSM‐5 diagnostic criteria for alcohol use disorder; 3. Currently in the withdrawal period with a CIWA‐Ar score of >=16 points; 4. The doctor assesses that benzodiazepines are suitable for treatment. 5. Sign the informed consent form.