A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk Aim 3

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
Between 2015 and 2019, overdose deaths translated to 1.25 million years of life lostamong adolescents and young adults (youth) aged 12 to 24 years, and the percent change infatal overdose rates among adolescents ages 14 to 18 was higher than adults between 2019and 2020.3‐5 Primary care providers are uniquely positioned to provide evidence‐basedinformation to youth to both improve awareness of overdose risk (individual benefit) andsimultaneously ensure that youth are prepared to recognize and respond to an overdose(public health benefit). However, currently there is no evidence‐based intervention forpediatric primary care to reduce youth overdose risk and ensure youth can recognize andrespond to an overdose.To address the gap in evidence‐based overdose prevention interventions for youth, wepropose a randomized controlled trial (RCT) to evaluate the efficacy of a brief universaloverdose prevention intervention in pediatric primary care. We will enroll 24 providersand 624 youth patient participants randomized (at the provider level) to receive eitherthe brief overdose prevention intervention or usual care.
Epistemonikos ID: 766e552bf6ff4a6661d36c9cdf4525cf2ac10d9e
First added on: Sep 01, 2026