Clinical Performance of Two HEMA-Free Universal Adhesive Systems

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2026
This randomized controlled clinical trial aims to compare the 12-month clinical performance of two HEMA-free universal adhesive systems for restoring anterior cervical carious lesions. Participants will be randomly allocated (1:1) to receive restorations using either a two-bottle HEMA-free universal adhesive (G2-Bond Universal) or a one-bottle HEMA-free universal adhesive (BeautiBond Xtreme), both applied in self-etch mode. The primary outcome is restoration retention, while secondary outcomes include marginal adaptation, marginal discoloration, and postoperative sensitivity, evaluated at baseline (24 hours), 6 months, and 12 months using the modified USPHS criteria.
Epistemonikos ID: 7657e5be784bc2e7bb7a2ed474ed861ebcf705ba
First added on: Jul 28, 2026