Dose Ranging Study of Ferroquine With Artesunate in African Adults and Children With Uncomplicated Plasmodium Falciparum Malaria

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2009
Primary objective: To assess the Day 28 efficacy defined as the percentage of patients with no parasitic recrudescence, of 3 treatment groups - 3 dose levels of ferroquine associated with artesunate - for a 3-day treatment. Secondary objectives: * To assess the efficacy of ferroquine at one dose level alone for a 3-day treatment. * To assess the clinical safety of 4 treatment groups - 3 dose levels of ferroquine associated with artesunate and one dose level of ferroquine alone. * To assess pharmacokinetics parameters of ferroquine and its metabolites along sparse sampling schedules.
Epistemonikos ID: 760964ef4c3a61231dab95c103564dcfe93a07ca
First added on: May 05, 2024