Is the clinical efficacy of epidural diamorphine concentration-dependent when used as analgesia for labour?

Authors
Category Primary study
JournalBritish journal of anaesthesia
Year 2005
BACKGROUND: The physicochemical properties of diamorphine (3,6-diacetylmorphine) enhance its bioavailability compared with more lipid-soluble opioids when administered into the epidural space. However, the influence of concentration, volume or mass on the clinical efficacy of diamorphine is not known. METHOD: In this double-blind, randomized, prospective study, 62 women in active labour and
Epistemonikos ID: 7574bf2432383d7568a561b9582beeb7dce68900
First added on: May 13, 2022