Examining the effects of Ionix Supreme on stress, mood, energy and anxiety.

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2017
INTERVENTION: Ionix Supreme liquid Oral liquid, 60mL daily for 4 weeks Medicinal ingredients include (per 30ml) Chinese Wolfberry 100 mg Betaine hydrochloride 20mg Velvet‐bean 30 mg Methylsulfonylmethane, synthetic 20mg Maca 10 mg Shilajeet 20mg DL‐alpha‐Lipoic acid 25mg Siberian‐ginseng 25 mg Ashwagandha 30 mg Schisandra 15 mg Tribulus 20 mg Bacopa 25mg Chebulic myrobalan 25mg Roseroot 30mg Indian‐gooseberry 25mg Niacinamide 13mg Vitamin B6 6mg Zinc 5mg Vitamin B2 4mg Ginger 5mg Vitamin b12 120mcg Yellow rhododendron 25mg Non‐medicinal ingredients: Kiwi fruit extract, watermelon juice, Hibiscus flower, Silica, alfalfa extract, Blueberry extract, Stevia leaf, DL‐malic acid, apple flavour, apple juice, sodium chloride, Water, molasses, potassium sorbate, potassium sorbate, sodium citrate Compliance will be measured by measurement of returned liquid and by a treatment taking log CONDITION: Anxiety Cognitive performance Stress PRIMARY OUTCOME: Perceived Stress ; Measured using the Perceived Stress Scale SECONDARY OUTCOME: Assessment of blood safety parameters ; Measured by Kidney and Liver function tests Brain Imaging ; A sub‐group will complete functional MRI task and MRS scan ; Assessment of the biochemical changes in the brain due to the intervention ‐ measured by Magnetic Resonance Spectroscopy (MRS) Brain Imaging. ; A sub‐group will complete functional MRI task and MRS scan ; Functional MRI scans will measure changes in the bold response during the RVIP and n‐back tasks. Changes in blood vitamin status ; measured by Vitamin B6, B12 and Red Cell Folate Changes in cognition measured by CogTrack Changes in subjective stress, measured on the State Trait Anxiety Inventory ‐ State version (STAI‐S), after completing the cognitive tasks Changes on the General Health Questionnaire (GHQ) Changes on the Profile of Mood states (POMS) ; Changes on the workplace stress questionnaire Effects on Cognition ; Measured by Purple multitasking framework Effects on biochemical measures from blood samples. ; Oxidative stress markers (F2 Isoprostanes, High Sensitivity C‐Reactive Protein (HsCRP) and Fibrinogen). ; Stress hormone measurement ; Measured in saliva cortisol changes in subjective mood and stress after completing the cognitive tasks, measured by the Bond‐Lader Visual analogue scales. INCLUSION CRITERIA: Fluent in written and spoken English In good general health Normal or corrected to normal vision
Epistemonikos ID: 75670fb167f0abd6d8498c32adb3aa354dd70557
First added on: Aug 25, 2024