The effect of exercise and nutrition on structural and functional systems in the elderly brain

INTERVENTION: Participants are randomized into two groups with different nutritional supplementation: 1. Intervention group: This group will take 13.5 ml of omega‐3 fatty acid supplementation daily for 26 weeks at home 2. Control group: This group will take 13.5 ml of olive oil supplementation daily for 26 weeks at home After 16 weeks, all participants follow 10 weeks of guided video‐game‐based physical exercise. Training sessions take place three times per week for 30 minutes. For the video‐game training, the participant follows the step instructions presented on a computer screen. Participants are standing on a pressure‐sensitive platform, which records right and wrong movements. Participants are accustomed slowly to the exercise and are continuously monitored by the instructors. CONDITION: People over 65 years, healthy (self‐report), and living independently or in a community residence ; Not Applicable PRIMARY OUTCOME: Current primary outcome measures as of 24/02/2016:; 1. Structural level:; 1.1. Transcranial magnetic stimulation: Motor evoked potential in M.tibialis anterior ; 2. Functional level:; 2.1. Electroencephalography: Event related potential and frequency band distribution ; 2.2. Cognitive test: Test for Attentional Performance (TAP); All measures are assessed pre‐intervention and after intervention.; ; Previous primary outcome measures:; 1. Structural level:; 1.1. Transcranial magnetic stimulation: Motor evoked potential in M.tibialis anterior ; 2. Functional level:; 2.1. Electroencephalography: Event related potential and frequency band distribution ; 2.2. Cognitive tests: Test for Attentional Performance (TAP) and Attention Network Test (ANT); All measures are assessed pre‐intervention and after intervention. SECONDARY OUTCOME: 1. Gait parameters:; 1.1. Temporal and spatial gait parameters are assessed with the Physilog®; 2. Prevention of falls:; 2.1. Icon Falls Efficacy Scale International (Icon‐FES‐I) questionnaire is used as a measure of 'concern' about falling, to determine the transfer effects of training to activities of daily living; 3. Mental state and depression:; 3.1. Mini Mental State Examination (MMSE); 3.2. Geriatric Depression Scale (GDS): symptoms of depression are recorded. The German version of the GDS has a good validity and reliability; 4. Blood samples measuring fatty acid; ; All measures are assessed pre‐intervention and after intervention. In addition, blood samples are measured after 16 weeks. INCLUSION CRITERIA: 1. Age above 65 years 2. Live independently or in a residency dwelling 3. Non‐smoker 4. Healthy (self‐reported)