Platelet-Rich Plasma Alone Versus PRP Plus Low-Intensity Shock Wave Therapy for Erectile Dysfunction

Erectile dysfunction is a common condition that may result from vascular, neurological,hormonal, psychological, or medication‐related factors. Platelet‐rich plasma (PRP) andlow‐intensity extracorporeal shock wave therapy (Li‐ESWT) are regenerative treatmentapproaches that may improve erectile function through mechanisms involving angiogenesis,tissue repair, and improvement of penile vascular function.This randomized prospective study will compare the efficacy and safety of PRP injectionalone with combined PRP injection and Li‐ESWT in men with erectile dysfunction. A totalof 80 participants will be randomly assigned to two groups. One group will receive PRPinjections alone, while the other group will receive PRP injections combined withLi‐ESWT. Participants will be followed after treatment to assess changes in erectilefunction, erection hardness, penile blood flow, patient satisfaction, andtreatment‐related adverse events.The study hypothesis is that adding Li‐ESWT to PRP therapy will result in greaterimprovement in erectile function than PRP therapy alone.