A study to find out whether histaglobulin injections relieve symptoms of long lasting hives better than anti-allergy tablets

INTERVENTION: Intervention1: Histaglobulin with Rescue Antihistamines: 1 ml of injection Histaglobulin will be given as weekly subcutaneous injection for 8 weeks. Patients will be advised to take oral tablet Levocetrizine 5 mg as and when required, not exceeding 4 times the daily dose that is 20 mg. Control Intervention1: Antihistamines: Patients will receive oral Levocetrizine tablet for 8 weeks. Treatment will be initiated at a dose of 5 mg once daily, if no adequate relief, dose can be increased stepwise upto 4 times the initial dose that is maximum upto 20 mg. CONDITION: Health Condition 1: L501‐ Idiopathic urticaria PRIMARY OUTCOME: Change in Urticaria Activity Score from baseline to week 24.Timepoint: Urticaria Activity Score will be calculated at baseline, 1,2,3,4,5,6,7,8 weeks and then at 12, 16 and 24 weeks. SECONDARY OUTCOME: Recording of adverse effects of Histaglobulin injection at each follow up visit.Timepoint: 1,2,3,4,5,6,7,8 and then at 12,16 and 24 weeks. Total number of rescue antihistamine doses required in patients receiving Histaglobulin. ; Timepoint: 1,2,3,4,5,6,7,8 weeks and then at 12, 16 and 24 weeks. INCLUSION CRITERIA: Diagnosed cases of chronic urticaria with active disease who are willing to give written informed consent for participation will be recruited in study