Effect of Landiolol as an adjunct to Primary Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction

INTERVENTION: Intraveous landiolol administation Placebo CONDITION: Acute myocardial infarction PRIMARY OUTCOME: Estimated infarct size (AUC of creatine kinase) SECONDARY OUTCOME: 1) Estimated infarct size (AUC of CK‐MB); 2) Infarct size on 99mTc‐MIBI SPECT INCLUSION CRITERIA: 1) chest pain more than 30 min 2) 0.1mV ST‐segment elevation in 2 contiguous ECG leads 3) admission to hospital within 12 hours of symptom onset 4) tachycardia of more than 80 beats/min 5) First episode of anterior STEMI 6) emergent primary percutaneous coronary intervention