A clinical trial of phenelzine in anxiety depressive and phobic neuroses.

A double-blind clinical trial of phenelzine and diazepam against placebo and diazepam in 117 neurotic patients over a 4-wk period showed phenelzine to be superior to placebo on 3 rating scales (global rating, self-rating anxiety, and Hamilton Anxiety Scale) in some groups of patients who completed the trial. Findings suggest that phenelzine may exert a beneficial effect on some as yet undefined features of anxiety and depression which were not revealed by a multiple regression analysis of clinical symptomatology or premorbid personality. (32 ref) (PsycInfo Database Record (c) 2021 APA, all rights reserved)