Effect of Procalcitonin Guidance for Duration of Antibiotic Therapy on Antibiotics Use in Aspiration Pneumonia Randomized Controlled Trial

INTERVENTION: Decide the duration of antibiotics therapy based on the level of procalcitonin on admission. Decide the duration of the antibiotics therapy according to standard protocol. Antibiotics use is continued until decline of fever, normalization of WBC count, improvement of radiological findings and decrease in the level of C‐reactive protein are observed. CONDITION: aspiration pneumonia PRIMARY OUTCOME: To prove the noninferiority of procalcitonin‐guided protocol about the adverse outcomes of death, recurrent of aspiration pneumonia within 2 weeks. SECONDARY OUTCOME: Reduction of antibiotics exposure and adverse effect from antibiotics. INCLUSION CRITERIA: (1) Hospital admitted patients with a diagnosis of aspiration pneumonia by clinical history and radiorogical appearance. (2) One month or more passes from the last pneumonia treatment for the relapse cases. (3) The ventilator use is not scheduled for the pneumonia treatment.