The Effect of Oat Cream on skin reaction caused by radiotherapy

INTERVENTION: At the first time of beginning radiotherapy we will recommend to patients use the cream which prepared from oat extract, three times a day each 8 hours daily (TDS), in the radiotherapy area, amount of one finger (FTU) will be applied uniformly with the index finger ( considerably in different patients based on the extent of the lesion, this unit can be doubled) and for 3 hours, they must avoid washing the area. In the control group patients will use placebo (extract‐free cream base). Intervention 1: At the first time of beginning radiotherapy we will recommend to patients use the cream which prepared from oat extract, three times a day each 8 hours daily (TDS), in the radiotherapy area, amount of one finger (FTU) will be applied uniformly with the index finger ( considerably in different patients based on the extent of the lesion, this unit can be doubled) and for 3 hours, they must avoid washing the area. Intervention 2: In the control group patients will use placebo (extract‐free cream base). Placebo Treatment ‐ Drugs CONDITION: Breast Cancer. ; Malignant Neoplasm of Breast Malignant Neoplasm of Breast SECONDARY OUTCOME: Drainage, Infection, Cellulitis. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Examination by a physician. Patchy and Distribution Moist Desquamation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Examination by a physician. INCLUSION CRITERIA: INCLUSION CRITERIA: Women with breast cancer; Without any skin lesion. Exclusion criteria: Patients with uncontrolled diabetes; Acquired immunodeficiency syndrome; A history of allergy to medicinal plants. PRIMARY OUTCOME: Burning sensation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient and using a researcher‐made questionnaire. Changes in daily activities. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient. Dry desquamation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher‐made questionnaire. Erythema. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher‐made questionnaire. Itching. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient and using a researcher‐made questionnaire. Tenderness. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient. The grade of skin reaction caused by radioytherapy. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher‐made questionnaire.