Diastolic Heart Failure Management by Nifedipine (DEMAND)

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2010
INTERVENTION: Intervention Conventional therapy plus nifedipine: participants will receive 10 to 60 mg of sustained‐release nifedipine once a day until December 2014 Control Conventional therapy CONDITION: Diastolic Heart Failure PRIMARY OUTCOME: Heart failure clinical composite response endpoint SECONDARY OUTCOME: Death; Cardiovascular death; Hospital admission; Hospital admission for cardiovascular disease; Hospital admission for worsening heart failure; Hospital admission for acute myocardial infarction, angina, coronary artery bypass grafting and percutaneous coronary intervention; Stroke INCLUSION CRITERIA: 1) Heart failure with history of hypertension and/or coronary artery disease 2) LVEF > or = 50% on echocardiography 3) Without taking nifedipine 4) 20 years and older 5) Inpatient and outpatient 6) Male and female
Epistemonikos ID: 6fd707151d7f68cbe3f328adf15e36a3546e628b
First added on: Aug 22, 2024