Effects of glycopyrrolate and atropine combined with antacid on gastric acidity.

Authors
Category Primary study
JournalBritish journal of anaesthesia
Year 1981
Glycopyrrolate, atropine or saline were administered i.v. with oral magnesium trisilicate 1 h before induction of anaesthesia to patients about to undergo Caesarean section. Both anticholinergics greatly reduced gastric acidity. It is suggested that glycopyrrolate should be used in combination with antacid therapy before obstetric anaesthesia and puerperal tubal ligation because of its prolonged duration of action, effect on gastric secretion and failure to cross the placental barrier.
Epistemonikos ID: 6f7b7b5197a02ae468a5e16e71fd0e4531f851b1
First added on: Oct 27, 2016