Effects, Safety, and Cost Efficacy of Controlled-Release Oxycodone for Pain Control in Transarterial Chemoembolization Therapy for Patients with Liver Cancers

INTERVENTION: B:20mg controlled‐release oxycodone given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE;A:10mg controlled‐release oxycodone given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE;C:placebo pills (containing 100 mg Vitamin C) given from one hour before chemoembolization (TACE) therapy and every 12 hours until 48hours after TACE; CONDITION: liver cancer PRIMARY OUTCOME: pain score (NRS); SECONDARY OUTCOME: morphine consumption;life qualit; INCLUSION CRITERIA: patients with age of 18 or older, scheduled for TACE