Comparing two medicine for pain relief after lower limb surgery aiming to find which one provides better and longer lasting pain relief with fewer side effects

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Group BF: Group BF will receive 15 ml of Bupivacaine and 50 mcg of Fentanyl and pain will be assessed by VAS score Control Intervention1: Group BN: Group BN will receive 15 ml of bupivacaine and 10 mg of Nalbuphine and pain will be assessed with VAS score CONDITION: Health Condition 1: 4‐ Measurement and Monitoring PRIMARY OUTCOME: 1.Postoperative analgesia by Visual Analog scale ; 2.To measure the need for rescue analgesia ; Timepoint: 1.Postoperative analgesia by Visual Analog scale ; 2.To measure the need for rescue analgesia ; SECONDARY OUTCOME: 1. Hemodynamic parameters including HR, MAP. ; 2. Postoperative complication related to Fentanyl & Nalbuphine ; 3. Level of sedation using Ramsay Sedation Score ; 4. Patient satisfaction using Likert scale.Timepoint: Baseline ,Every 5 minutes till 40 minutes then every 10 minutes till 90 minutes INCLUSION CRITERIA: Patients aged 25 to 60 years. Gender both males and females ASA grade 1 and 2 Scheduled for elective lower limb orthopedic surgeries Patient providing written informed consent
Epistemonikos ID: 6edfe7fe9b8cc38b50dad33c2271201de6bf813a
First added on: Oct 08, 2026