The Clinical Efficacy Evaluation and Mechanism of Action Study of Hai Tong Pi Formula Fumigation and Washing as Adjuvant Therapy for Knee Osteoarthritis

INTERVENTION: Experimental Group:Basic treatment + Oral non‐steroidal anti‐inflammatory and analgesic drugs + Eurya emarginata decoction for fumigation and washing;Control Group:Basic treatment plus oral nonsteroidal anti‐inflammatory and analgesic drugs.;Health Group:No intervention measures; CONDITION: Knee osteoarthritis PRIMARY OUTCOME: The response rate of the Visual Analogue Scale for Pain; SECONDARY OUTCOME: Western Ontario and McMaster Universities Osteoarthritis Inde XTotal Score;Western Ontario and McMaster Universities Osteoarthritis Inde XSubscale Score;Quality of Life Score (SF‐12);Traditional Chinese Medicine syndrome score; INCLUSION CRITERIA: 1) Patients who meet the diagnostic criteria for knee osteoarthritis (unilateral or bilateral); 2) Patients who meet the diagnostic criteria for cold‐damp obstruction syndrome in traditional Chinese medicine for knee osteoarthritis; 3) Patients aged between 50‐70 years, with no gender restrictions; 4) Patients with a disease duration of knee osteoarthritis = 3 months; 5) Knee joint X‐ray K‐L grading belongs to Grade I‐II; 6) The staging of knee osteoarthritis belongs to the initial or early stage; 7) Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) score < 12 points; 8) Visual Analog Scale (VAS) score between 3 and 5 points (inclusive); 9) Signed informed consent.