Statin Therapy in Ischemia-Reperfusion Injury during coronary artery bypass grafting.

INTERVENTION: Rosuvastatin 40mgs orally at 36 hours and 12 hours pre CABG and then rosuvastatin 40 mgs daily for 7 days post CABG. CONDITION: Post CABG ischemia reperfusion injury (IRI) PRIMARY OUTCOME: Myocardial Infarct (MI) size as assessed by CMR late gadolinium‐enhancement SECONDARY OUTCOME: Biochemical markers of myocardial injury will be assessed by calculating the total area under the curve of the cardiac enzyme levels (CK, CKMB and Hs Troponin T) taken over an 120 hour period. INCLUSION CRITERIA: Adult patients who are scheduled to undergo elective on‐pump CABG with or without aortic valve replacement. For patients on statins pre‐CABG, statin dose must be unchanged for 30 days pre‐CABG.