5-Fluorouracil and Calcipotriene for Field Treatment of Actinic Keratoses

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
Combination field therapy with 5-fluorouracil and calcipotriene (5FU/C) has become standard of care among dermatologists for the field treatment of diffuse actinic keratoses (AKs). Data suggest that the addition of calcipotriene elicits a sustained T cell memory allowing for both short and long-term AK clearance. Our objective is to evaluate the efficacy, as well as, document the timing, severity and duration of local cutaneous reactions to topical treatment with 5FU/C for the treatment of AKs.
Epistemonikos ID: 6e4a7e3628ff5588b16f3d9cf9eb6ebdb00e5b71
First added on: Sep 01, 2026