Effect of Integrated Traditional Chinese and Western Medicine on T Lymphocyte Subsets of Patients with Normal Type of COVID-19/ 中西医结合治疗对普通型新型冠状病毒肺炎患者T淋巴细胞亚群的影响

Objective To investigate the effect of integrated traditional Chinese and Western medicine on peripheral blood T lymphocyte subsets in patients with normal type of coronavirus disease 2019 (COVID-19) Methods Six- ty-seven patients diagnosed with normal type of COVID-19 were collected and divided into treatment group (33 cases) and control group (34 cases) The control group was treated with conventional oxygen therapy，antiviral，anti-inflammatory，and symptomatic treatment;and no drug was given during the recovery period On the basis of the control group，the treatment group was given with FeiyanYihao Chinese medicine granules throughout the whole course The peripheral blood T lymphocyte subsets were compared between the two groups of patients at the beginning (first week) and the recovery period (fourth week) Results The CD3+ ，CD4 + ，and CD8+ T lymphocyte counts of the patients decreased in the early stages of onset and increased during the recovery period The increase of CD3 + and CD4+ cells in the treatment group was significantly prominent than that in the control group ( P ＜ 0 05) CD4 + /CD8 + was significantly increased in the treatment group，and decreased in the control group ( P ＜ 0 05) Conclusion The combination of traditional Chinese and Western medicine can regulate the expression of T lymphocytes and promote the recovery of immune function in patients It is an effective treatment for the treatment of normal type of COVID-19．