Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain

The goal of this clinical trial is to compare submucosal Cryotherapy with different anti-inflammatory drugs in the reduction of post-endodontic pain in upper premolars with symptomatic irreversible pulpitis. The main question it aims to answer is: Is there is a difference in post-endodontic pain intensity following submucosal cryotherapy or anti-inflammatory drugs injection in patients with symptomatic irreversible pulpitis? Participants will undergo root canal treatment preceded by preoperative injection of cold saline (cryotherapy) or preoperative injection of anti-inflammatory drugs Researchers will compare \[Cryotherapy, Non steroidal anti-inflammatory drugs, steroids and no intervention\] to see the intensity of post-endodontic pain.