Grape Seed Extract Supplementation on Cycling Time-to-Exhaustion Performance.

To address the physical fatigue and muscle recovery demands in endurance exercise, this study evaluates Grape Seed Extract (GSE) as a potential ergogenic aid. The research aims to investigate whether short-term, high-dose GSE supplementation (1,800 mg/day for 7 days) prolongs cycling time-to-exhaustion (TTE) at 75% VO2max while attenuating exercise-induced muscle damage, metabolic stress, and mood disturbance in collegiate athletes. This study seeks to enhance high-intensity endurance performance and support the development of functional botanical anti-fatigue supplements.