Pulmonary Vascular Effects of Respiratory Rate & Carbon Dioxide

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2013
The purpose of this protocol is to perform serial physiological measurements and blood testing on mechanically ventilated patients comparing conditions of eucapnia and hypercapnia in the same patient. We will be testing two hypotheses: (1) while administering inspired carbon dioxide (CO2), eucapnia achieved by high respiratory rate (EHR) significantly decreases pulmonary artery pressures compared to hypercapnia with a lower respiratory rate (HLR), and (2) that EHR decreases myocardial strain compared to HLR.
Epistemonikos ID: 6c6bdc23fa368cb6d365ad5b99bc6ec01f1370ce
First added on: May 11, 2024