The combination effect of five herbal drugs" Peganum harmala, Quercus infectoria,Vaccinium myrtillus, Citrullos colocynthis, Securigera securidaca" on blood glucose in adults with type 2 diabetes mellitus

INTERVENTION: Intervention 1: Intervention group: capsule contains 500 mg of combination of 5 herbal drug, twice daily for 8 weeks. Intervention 2: Placebo group: flour of bean capsul, twice daily for 8 weeks. Intervention group: capsule contains 500 mg of combination of 5 herbal drug, twice daily for 8 weeks Placebo Placebo group: flour of bean capsul, twice daily for 8 weeks Treatment ‐ Drugs CONDITION: diabetes mellitus. ; Non‐insulin‐dependent diabetes mellitus Non‐insulin‐dependent diabetes mellitus PRIMARY OUTCOME: FBS. Timepoint: before and 4 and 8 weeks after intervention. Method of measurement: laboratory. HbA1C. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory. SECONDARY OUTCOME: Lipid profile. Timepoint: before and 4 and 8 weeks after intervention. Method of measurement: laboratory. Serum insulin. Timepoint: before and 8 weeks after intervention. Method of measurement: laboratory. Weight. Timepoint: before and 8 weeks after intervention. Method of measurement: weight Scale. INCLUSION CRITERIA: INCLUSION CRITERIA: age 30 to 80, HbA1C 6.5 to 8% .Exclusions criteria: Immune deficiency, pregnancy and lactation, cardiovascular disease, currently receiving corticosteroids and thiazide, uncontrolled thyroid dysfunction, acute infection ,history of diabetic ketoacidosis , Cr>1.5 for male, Cr>1.2 for female, acute hepatitis, cirrhosis, proliferative retinopathy and severe weight loss (at least 10% during last 6 months)