Myocardial preconditioning in coronary artery bypass surgery

INTERVENTION: The stimulus for RIPC that will be used will be inflation of a blood pressure cuff placed around the upper arm. The cuff will be inflated to 200 mmHg for 5 minutes after which it will be deflated for 5 minutes. This procedure will be repeated upto three times in total based on randomisation protocol. In the control arm, an uninflated blood pressure cuff will be placed on the patients's upper arm for the duration of 30 minutes. CONDITION: Topic: Cardiovascular; Subtopic: Cardiovascular (all Subtopics); Disease: Cardiovascular ; Circulatory System ; Myocardial injury PRIMARY OUTCOME: Myocardial injury, assessed by Troponin T and creatine kinase myocardial band (CK‐MB) levels over the 72 hours post‐CABG surgery. SECONDARY OUTCOME: 1. Ionotropic score, measured at first week post‐operative period; 2. Ventilation times, measured at the timepoint when patients are weaned from ventilator in the ITU (first 2 days post‐operative period); 3. Intensive care unit (ITU) stay, measured at first week post‐operative period INCLUSION CRITERIA: 1. Aged over 18 years 2. Patients undergoing coronary bypass surgery with or without concomitant heart valve surgeries 3. Male and female patients