ReJUICE your pain: The effect of dietary advice and a dietary supplement on pain outcomes in people experiencing chronic pain

INTERVENTION: Two intervention components will be tested: 1) Personalized dietary advice provided via telehealth and 2) Dietary supplement. The dietary supplement is a fruit juice. Two fruit juices will be used 1) Active fruit juice (high in anthocyanins) and 2) Placebo fruit juice (no anthocyanins). Participants will be randomized into one of four groups Study arm 1: Personalized dietary advice and active fruit juice Study arm 2: Personalized dietary advice and placebo fruit juice Study arm 3: Waitlist control and active fruit juice Study arm 4: Waitlist control and placebo fruit juice Personalized dietary advice: Participants will receive up to three 30‐45 minute consultations (2 recommended, 1 optional) with an Accredited Practicing Dietitian (APD). This will be provided via Avaya Scopia (the telehealth software used by Hunter New England health) or via phone calls. Prior to the consult, participants will complete the Australian Eating Survey (AES) Food Frequency Questionnaire which generates a report comparing dietary intake to national guidelines. Participants will be sent their AES report prior to the first consultation. They will also be asked to complete a personalised nutrition questionnaire (PNQ) to identify factors which may affect their eating behaviors which will allow the APD to prioritize barriers that may affect each participant. There is a toolbox associated with the PNQ which lists intervention strategies and resources linked with each factor. The APD used the PNQ and toolbox to discuss strategies and goal setting. A summary of the session and links to relevant resources will be emailed to each participant at the end of the session. The resources include websites and handouts which were sourced from government departments, The Dietitians Association of Australia, Nutrition Education Materials Online, Australian Healthy Food Guide and Practice‐based Evidence in Nutrition Fruit juice: participants will receive 42X 250ml bo CONDITION: Anaesthesiology ‐ Pain management Chronic pain; ; Chronic pain Neurological ‐ Other neurological disorders PRIMARY OUTCOME: Feasibility measured using a questionnaire provided to participants at the final session. The questions included were designed for the study and include a series of likert scale based questions with answers ranging from strongly disagree to strongly agree or very unsatisfied to very satisfied; ; [End of the intervention (6 weeks)] Participants pain self‐efficacy which will be measured using the Pain Self Efficacy Questionnaire ; [End of the intervention (6 weeks)] Participants pain severity which will be measured using the Brief Pain Inventory; [End of the intervention (6 weeks)] SECONDARY OUTCOME: Inflammation biomarkers (CRP, IL‐6, TNFa)[End of the intervention (6 weeks)] Arterial stiffness measured using BP+ supra systolic oscillometric central blood pressure monitor [End of the intervention (6 weeks)] Blood pressure measured using BP+ supra systolic oscillometric central blood pressure monitor [End of the intervention (6 weeks)] Body composition (InBody 770 Body composition and body water analyser)[End of the intervention (6 weeks)] Height ‐ automatic stadiometer[End of the intervention (6 weeks)] Participants pain catastrophising which will be measured using the Pain Catastrophising Scale INCLUSION CRITERIA: Referred to Hunter Integrated Pain Service for the treatment of chronic pain Access to reliable broadband internet Able to attend two in person measurement sessions at the University of Newcastle Willing to provide fasting blood sample ; [End of the intervention (6 weeks)] Presence of food addiction traits, YALE food addiction scale[End of the intervention (6 weeks)] Serum antioxidant capacity ( Ferric Reducing Ability of Plasma)[End of the 6 week intervention] Serum antioxidant capacity (Oxygen Radical Absorbance Capacity)[End of the intervention (6 weeks)] Skin colour, presence of caroteniods in the skin ‐ photographs were taken on the palm of the hand, and either side of the elbow using a spectrophotometer.[End of the intervention (6 weeks)] Waist circumference (measured by researcher using measuring tape half way between top of hip and bottom rib)[End of the intervention (6 weeks)] Weight (InBody 770 Body composition and body water analyser)[End of the intervention (6 weeks)]