Efficacy and Outcomes of Continuous Theta Burst Stimulation Based on Functional Near-Infrared Spectroscopy in Post-Stroke Comprehension-Impaired Aphasia: a Clinical Study

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: The control group:sham‐CTBS;The experimental group:Continuous theta?burst stimulation (cTBS); CONDITION: Post‐stroke aphasia (PSA) PRIMARY OUTCOME: Resting‐state functional connectivity (FC) values between channels;Beta coefficients (ß values) from the general linear model (GLM); SECONDARY OUTCOME: Montreal Cognitive Assessment score;Western Aphasia Battery, WAB;Modified Barthel Index;Mini‐Mental State Examination; INCLUSION CRITERIA: 1. Patients diagnosed with post‐stroke aphasia; 2. documented stroke history and imaging evidence (e.g., CT, MRI) in medical history collection, indicating comprehension‐impaired aphasia following stroke; 3. comprehension‐impaired patients with fluency scores of 5–10 on the Spontaneous Speech subscale and scores of 0–6.9 on the Auditory Comprehension subscale of the Western Aphasia Battery (WAB); no specific requirements for Repetition and Naming subscale scores; 4. aged 18–80 years; 5. first‐ever stroke; 6. stroke duration of 1–6 months; 7. left‐sided stroke lesion; 8. at least primary school education; 9. provision of signed informed consent for treatment.
Epistemonikos ID: 693c6bff210a6e1ad0e1348b7cc878b7071498d3
First added on: Oct 08, 2026