Clinical effect and mechanism of acupuncture-assisted methadone dose reduction in MMT patients

INTERVENTION: sham acupuncture group:sham acupuncture;acupuncture group:acupuncture; CONDITION: opioid use disorder PRIMARY OUTCOME: Clinical Opiate Withdrawal Scale;effective rate of MMT reduction; SECONDARY OUTCOME: Pittsburgh sleep quality index;Visual Analogue Scales;Beck Anxiety Inventory;Beck Depression InventoryII‐II;Urine morphine test; INCLUSION CRITERIA: (1) Meet the diagnostic criteria for opioid use disorder in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM‐V). Diagnostic criteria; (2) 18 to 60 years old; (3) Currently receiving methadone maintenance therapy for at least 6 weeks; (4) A need for methadone reduction; (5) No acupuncture treatment in the past 3 months; (6) Sign the informed consent.