Effect of calcium injection on adequacy of uterus to return to normal muscle tone and thus stop bleeding during surgery for baby delivery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Calcium group: Calcium chloride therapy.: Will receive 10 ml of 10 percent calcium chloride intravenously, diluted with 40 ml of normal saline such that total volume is 50 ml.The study drug will be administered over 5 minutes starting at umbilical cord clamping via infusion pump at rate of 10 ml per min. Control Intervention1: Placebo: Normal saline: Will receive normal saline infusion in total volume of 50 ml.The infusion will be administered over 5 minutes starting at umbilical cord clamping via infusion pump at rate of 10 ml per min. CONDITION: Health Condition 1: O720‐ Third‐stage hemorrhage PRIMARY OUTCOME: Incidence of additional uterotonic drug requirement despite the oxytocin injection, during the surgery.Timepoint: During period starting from end of oxytocin injection to end of surgery. SECONDARY OUTCOME: Blood lossTimepoint: At end of surgery. INCLUSION CRITERIA: Women with preeclampsia scheduled for intrapartum caesarean delivery, defined as labor with or without oxytocin administration prior to cesarean delivery, using spinal anaesthesia.
Epistemonikos ID: 68b97571dddba3d267a6d887043783fd7f551584
First added on: Oct 08, 2026